The association of meat consumption and breast cancer risk: A case control study in a population of Iranian women

نویسندگان

  • Zeinab Karimi
  • Zahra Bahadoran
  • Anahita Houshiar-rad
  • Hamid-Reza Mirzayi
  • Bahram Rashidkhani
چکیده

Objective: Epidemiologic data do not provide consistent evidence for an association between consumption of meat and breast cancer risk. We conducted a hospital-based case-control study during April and July 2010 among Iranian women to investigate associations between dietary meat intake, its types and breast cancer risk. Methods: One-hundred consecutively recruited cases with newly diagnosed breast cancer were frequency matched to 175 controls by age. Dietary intake was assessed by using a validated semi-quantitative food frequency questionnaire. Odds ratios and 95% confidence interval were obtained by using multiple logistic regression models adjusted for various potentially confounding variables. Results: The mean age of participant was 46.2±8.9 and 45.9±9.4 y in cases and controls, respectively. After adjustment of potential confounders, no association was found between total meat intake and the odds of breast cancer, but the risk of breast cancer in the forth quartile of red meat intake, compared with first quartile, significantly increased (OR=2.43, 95% CI=1.115.32). Consumption of poultry > 212 g/week significantly decreased the risk of breast cancer. Higher intake of fish meat decreased the odds of breast cancer (P for trend<0.05), whereas higher intake of processed meat was accompanied with increased the risk of breast cancer (P for trend<0.05). Conclusion: We found a positive association between dietary intake of red meat and processed meat products with the odds of breast cancer, as well as protective effects of fish and poultry intake with breast cancer.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

ارتباط میزان مصرف لبنیات و پروتئین‌های حیوانی با سرطان پستان در زنان استان اصفهان

Background and Objective: Breast cancer is one of the most common cancers affecting women around the world and in Iran. A limited number of studies have been conducted on the relationship between dietary factors and breast cancer development in Iran. The aim of this study was to investigate the impact of dairy products and animal proteins consumption and breast cancer among women in the provinc...

متن کامل

Genetic polymorphisms in the estrogen receptor - α Gene codon 325(CCC}CCG) and risk of breast cancer among Iranian women: a case control study

  Abstract   Background: The Iranian breast cancer patients are relatively younger than their   Western counterparts. Evidence suggests that alterations in estrogen signaling pathways , including estrogen receptor-α (ER- α ), occur during breast cancer development in Caucasians. Epidemiologic studies have revealed that age-incidence patterns of breast cancer in Asians differ from those in Cauca...

متن کامل

Association of Obesity Related Genetic Variants (FTO and MC4R) with Breast Cancer Risk:a population-based case-control study in Iran

Background: The heterogeneous breast cancer is the most common cause of cancer-related mortality. Obesity defined by BMI is known as a major risk factor for breast cancer. Objective: The purpose of this study was to explore the role of obesity related-polymorphisms rs9939609 FTO and rs17782313 MC4R in breast cancer development. Materials and Methods: We obtained matched peripheral blood, serum ...

متن کامل

Association of CYP1A1 IIe462Val (rs1048943) Polymorphism with Breast Cancer in Iranian Women

Backgrounds and Aims: One member of the cytochrome P450 family, CYP1A1, is one of the genes involved in the metabolism of carcinogens and estrogen, which has been identified to be associated with breast cancer, as well. Considering the known effect of estrogen in different signaling pathways, disorders in these pathways will affect the risk of breast cancer. In this study, we evaluated the rela...

متن کامل

عوامل‌ مستعد کننده‌ سرطان‌ پستان‌

  Background : After lung cancer, breast cancer is the second cause of mortality among women. Although the prevalence of this disease has been increased, but the rate of mortality has not been changed during last three decades, this may be due to early diagnosis at the first stage of disease .   Objective : To determine risk factors of breast cancer in women.   Design : It was a case- control s...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2014